Robert Rosen wrote extensively about many scientific subjects, with a research stream that always circled back to the essential question of 'What is life?' Below you can access most of his published work, as well as some unpublished notes, including the primary ideas that led to the development of Life Itself I: Epistemology, and its intended sequel, Life Itself II: Ontology.
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Abstract biological systems as sequential machines

The study reveals a significant connection between (M,R)-systems and sequential machines, reformulating the theory to explore their intertransformability under environmental changes, emphasizing strong connectedness and proposing avenues for further research

Topics:

(M,R)-Systems
Category Theory
Sequential Machines
Dated
Article
1964

Abstract biological systems as sequential machines II- Strong connectedness and reversibility

The study reveals that (M,R)-systems, when viewed as sequential machines, often lack strong connectedness due to a small input alphabet relative to their state size, leading to the conclusion that most environmental structural changes may be irreversible or that many mappings in their formation are not physically realizable

Topics:

(M,R)-Systems
Category Theory
Sequential Machines
Dated
Article
1964

Abstract biological systems as sequential machines- III Some algebraic aspects

The totality of (M,R)-systems naturally forms a category, as demonstrated through their relationship with sequential machines

Topics:

(M,R)-Systems
Category Theory
Sequential Machines
Dated
Article
1966

Adjacent notes to the 1993 - 1994 bundle

Topics:

Category Theory
Mapping
Forgetful Functors
Reductionism
Dated
Typed notes
1993

Again, crucial 31JUL1993

Topics:

Bifurcation
Mapping
Reaction Network
Category Theory
Dated
Typed notes
1993
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