Robert Rosen wrote extensively about many scientific subjects, with a research stream that always circled back to the essential question of 'What is life?' Below you can access most of his published work, as well as some unpublished notes, including the primary ideas that led to the development of Life Itself I: Epistemology, and its intended sequel, Life Itself II: Ontology.
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A note on replication in (M,R)-systems

The condition for induced replication maps in (M,R)-systems imposes significant limitations on the category's complexity while providing a biologically interpretable framework for empirical validation and insights into their physical and biological manifestations

Topics:

(M,R)-Systems
Replication
Mapping
Genetics
Dated
Article
1966

A note on the cross-reactivity of antibodies

Each antibody acts as a "feature detector" for antigens, with the proportion of antigens bearing a single feature being 1/N, indicating that cross-reactivity influences the total number of features N, which typically require at least five amino acids in protein antigens

Topics:

Immune System
Modelling
Proteins
Dated
Article
1976

A note on the quantum-theoretic basis of primary genetic activity

This study supports a general theory of primary genetic processes by comparing its predictions with experimental data on DNA and RNA, while allowing for alternative interpretations of the information-bearing objects involved

Topics:

Genetics
DNA
Quantum
Information
Microphysical
Dated
Article
1963

A note on the structural stability of universal systems

Topics:

Dynamical Systems
Dated
Article draft
1974

A point of order and note on identity

Topics:

Logic
Causality
Formal Cause
Efficient Cause
Identity
Undated
Typed notes
Undated
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